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01 奈良県立医科大学 >
011 医学部 >
0112 紀要 >
01121 Journal of Nara Medical Association >
Vol.43 No.1 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10564/1930
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| タイトル: | THE EXPRESSION OF THE fms GENE AND THE GENE PRODUCT IN THYROID TUMOR |
| 著者: | Haga, Satomi
Inui, Masahiko
Matsuzuka, Humio
Katayama, Shouichi
Yamamoto, Hiroshi
Hiasa, Yoshio |
| キーワード: | human DNA
thyroid tumor
fms gene
fms gene product |
| 発行日: | 1992年2月29日 |
| 出版者: | 奈良医学会 |
| 引用: | 奈良医学雑誌 Vol.43 No.1 p.46-49 |
| 抄録: | The amplification of the fms gene DNA was investigated in 5 human thyroid tumors. No significant amplification or rearrangement was observed in tumor DNA. The expression of the fms gene product was also investigated in 20 thyroid tumor tissues embedded in paraffin using a polyclonal antibody to the fms oncogene product immunohistochemically. Ten out of 20 samples showed clearly positive, 6 out of 20 were weakly positive but 4 out of 20 were negative. Therefore, the fms oncogene might play an
important role for thyroid carcinogenesis, and it might also be of possible importance for understanding the mechanism of thyroid carcinogenesis. |
| URI: | http://hdl.handle.net/10564/1930 |
| ISSN: | 04695550
13450069 |
| 出現コレクション: | Vol.43 No.1
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