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01121 Journal of Nara Medical Association >
Vol.43 No.1 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/1930

Title: THE EXPRESSION OF THE fms GENE AND THE GENE PRODUCT IN THYROID TUMOR
Authors: Haga, Satomi
Inui, Masahiko
Matsuzuka, Humio
Katayama, Shouichi
Yamamoto, Hiroshi
Hiasa, Yoshio
Keywords: human DNA
thyroid tumor
fms gene
fms gene product
Issue Date: 29-Feb-1992
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.43 No.1 p.46-49
Abstract: The amplification of the fms gene DNA was investigated in 5 human thyroid tumors. No significant amplification or rearrangement was observed in tumor DNA. The expression of the fms gene product was also investigated in 20 thyroid tumor tissues embedded in paraffin using a polyclonal antibody to the fms oncogene product immunohistochemically. Ten out of 20 samples showed clearly positive, 6 out of 20 were weakly positive but 4 out of 20 were negative. Therefore, the fms oncogene might play an important role for thyroid carcinogenesis, and it might also be of possible importance for understanding the mechanism of thyroid carcinogenesis.
URI: http://hdl.handle.net/10564/1930
ISSN: 04695550
13450069
Appears in Collections:Vol.43 No.1

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