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Vol.43 No.1 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/1928

Title: 尿路性器悪性腫瘍におけるcirculating immune complexesの検討
Other Titles: ANALYSIS OF CIRCULATING IMMUNE COMPLEXES IN PATIENTS WITH UROGENITAL MALIGNANCIES
Authors: 松木, 尚
大園, 誠一郎
山口, 尚子
北川, 恒代
常深, 邦彦
越, 順規
三馬, 省二
平尾, 佳彦
岡島, 英五郎
米増, 國雄
佐々木, 隆子
栄田, 英根
実渕, 豊
Keywords: circulating immune complexes
urogenital malignancy
Issue Date: 29-Feb-1992
Publisher: 奈良医学会
Citation: 奈良医学雑誌 Vol.43 No.1 p.34-40
Abstract: The present investigation was conducted to examine the efficacy of the circulating immune complexes (CIC) in patients with urogenital cancer. A total of 62 patients including 10 cases of renal cell carcinoma, 7 of renal pelvic and/or ureteral cancer, 35 of bladder cancer, 9 of prostatic cancer and 1 of testicular cancer were examined. Twelve patients with urolithiasis, 11 with chronic nephritis, and 12 healthy volunteers were used as controls. CIC levels of the sera and urine in each case were determined by Clq solid-phase enzyme immunoassay technique developed by Japan Medical Laboratories Co., Ltd. CIC levels of the sera in patients with bladder cancer were significantly higher than those in healthy controls (p<0.05). According to the stage and grade of bladder cancer, CIC levels of the sera in Tla, grade 1 and grade 2 patients were significantly higher than those in healthy controls (p<0.05). CIC levels of the urine in patients with bladder cancer and chronic nephritis were significantly higher than those in healthy controls (p<0.05). According to the stage and grade of bladder cancer, CIC levels of the urine in Tla and grade 2 patients were higher than those in healthy controls (p<0.1). These results indicate that high levels of CIC of the sera and urine were present in patients with low stage and low grade bladder cancer. Further investigatins to analyze a tumor specific antigen and to make an antibody from the sample in patients with bladder cancer will be warranted.
URI: http://hdl.handle.net/10564/1928
ISSN: 04695550
13450069
Appears in Collections:Vol.43 No.1

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