当科における過去10年間(1981年~1991年)の顎・口腔領域悪性腫瘍症例の臨床統計的観察

Abstract

Clinico-statistical studies were performed on 202 patients with malignant tumors of the head and neck region from October 1981 to October 1991 in our department. 1) Of 202 patients, 130 were male and 72 were female (1.8:1). 2) Of all cases, 162 (80.2%) were mainly referred by private dental practitioners, physicians and surgeons. 3) Histopathologically, 169 cases (83.3%) were diagnosed as squamous cell carcinoma, 6 cases (3.0%) as adenoid cystic carcinoma, 5 cases (2.5%) as adenocarcinoma, 1 case (0.5%) as mucoepidermoid carcinoma and 7 cases (3.5%) as metastatic carcinoma to the oral region. 4) According to the TNM classification by UICC (1987), 164 squamous cell carcinomas were classified as 20 cases (12.2%) of T1, 69 cases (42.1%) of T2, 45 cases (27.4%) of T3 and 30 cases (18.3%) of T4, and further classified as 52 cases (31.7%) of N0, 68 cases (41.5%) of N1, 42 cases (25.6%) of N2 and 2 cases (1.2%) of N3. In the Stage classification, these were classified as 15 cases (9.1%) of Stage Ⅰ, 26 cases (15.9%) of Stage Ⅱ, 66 cases (40.2%) of Stage Ⅲ and 57 cases (34.8%) of Stage Ⅳ. Of 164 squamous cell carcinoma cases, 110 (67.1%) were treated by surgery combined with irradiation and chemotherapy, 27 (16.5%) by irradiation and chemotherapy, 6 (3.0%) by surgery combined with chemotherapy, 6 (3.0%) by surgery alone, 5 (3.0%) by irradiation alone, 5 (3.0%) by chemotherapy alone, 2 (1.2%) by surgery combined with irradiation and 3 cases (1.8%) were not treated. Using the Kaplan-Meier method, the 5-year survival rates were as follows : Stage Ⅰ : 82.1%, Stage Ⅱ : 80.7%, Stage Ⅲ : 60.3%, Stage Ⅳ : 26.6% and total cases : 60.2%.