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01 奈良県立医科大学 >
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01121 Journal of Nara Medical Association >
Vol.45 No.2 >
このアイテムの引用には次の識別子を使用してください:
http://hdl.handle.net/10564/1714
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タイトル: | 実験的肺空気塞栓に対する過換気の影響 |
その他のタイトル: | EFFECTS OF HYPERVENTILATION ON THE EXPERIMENTAL PULMONARY AIR-EMBOLISM OF DOGS |
著者: | 梁, 宗哲 |
キーワード: | pulmonary air-embolism acidosis pulmonary hypertension hyperventilation paradoxical air-embolism |
発行日: | 1994年4月30日 |
出版者: | 奈良医学会 |
引用: | 奈良医学雑誌 Vol.45 No.2 p.208-215 |
抄録: | We attempted to elucidate effects of hyperventilation in experimental pulmonary air-embolism of dogs. Pulmonary air embolism was produced by air infusion 0.1 ml/kg/min. for 10 minuten (0.1 ml/kg) via inserted pulmonary artery catheter ; endotracheal anesthetized dogs with fentanyl and vecuronium bromide under mechanical ventilation. We measured hemodynamic variables and pH, blood gas (arterial, mixed
venous blood) at baseline, post-air infusion and after recovered pulmonary artery pressure
(PAP). In addition PAP recovery-times were counted. As results, PAP recovery-times in
hyperventilation group (pH=7.50, PaCO₂=25 mmHg) were attenuated significantly compared with normoventilation (control) group (pH=7.40, PaCO₂=40 mmHg) ; these values were 14.2±5.2 min. versus 17.8±6.0 min. (n=8, p<0.05). On the threshould air volume of paradoxical air-embolism, we confirmed air bubbles in the left atrium and/or aorta with using transesophageal echocardiography and recognized 0.75±0.27 ml/kg (hyperventilation group), and 0.83±0.26 ml/kg (control) respectively ; there were no
significant differences related to the ventilation-modus. We concluded that recovery-time of elevated pulmonary artery pressure was attenuated with induced hyperventilation in the experimental air embolism, but that hyperventilation revealed no beneficial effects on the threshold air volume of paradoxical air-embolism. |
URI: | http://hdl.handle.net/10564/1714 |
ISSN: | 04695550 13450069 |
出現コレクション: | Vol.45 No.2
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