胃転移巣の免疫染色にて診断した原発性肺腺癌の1例

Abstract

We report a rare case of gastric metastasis from primary lung adenocarcinoma. A 64-year-old woman with a liver tumor had been admitted to our hospital for further examinations of a liver tumor. Chest CT showed lung tumor on the right upper lobe， and esophagogastroduodenoscopy showed verrucous erosion on the greater curve of the fornix. The histopathology of the liver tumor and the verrucous erosion revealed differentiated adenocarcinoma. The immunohistochemistry of both lesions were positive for TTF-1 and CK-7，and negative for CK-20，by which both liver and stomach lesions were diagnosed as metastases from the primary lung adenocarcinoma. She received chemotherapy，however she died 14 months after diagnosis. When the verrucous erosion on upper side of the stomach is found in a patient with malignant tumor in other organs，it should be considered as a metastatic tumor. Therefore histological examination is strongly recommended.