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Vol.54 No.2 >

Please use this identifier to cite or link to this item: http://hdl.handle.net/10564/104

Title: 高度の血小板増多を呈した骨髄異形成症候群の1例
Other Titles: A CASE OF MYELODYSPLASTIC SYNDROME WITH REMARKABLE THROMBOCYTOSIS
Authors: 団野, 大介
神野, 正敏
藤本, 眞一
中村, 忍
川田, 啓之
原田, 幸児
中谷, 公彦
橋本, 俊雄
Keywords: MDS
RAEB-T
thrombocytosis
Issue Date: 30-Apr-2003
Publisher: 奈良医学会
奈良県立医科大学
Citation: Journal of Nara Medical Association Vol.54 No.2 p.125-130
Abstract: A 69-year-old woman was admitted to our hospital because of gingival bleeding on May 1997. She had been our outpatient for treatment of angina pectoris since 1987. She had had stomatorrhagia and slight fever since April 1997. On the present admission, she had normocytic normochromic anemia and myeloblast with Auer bodies in her peripheral blood. She also had dysplasia in her marrow cells. She was diagnosed as having MDS (RAEB-T). Although MDS is usually associated with pancytopenia, this patient had remarkable thrombocytosis. The 5q-syndrome sometimes has thrombocytosis. However, her chromosome analysis showed normal karyotype, and she did not have chromosome aberration. Thrombopoietin and IL-6 which are known as growth factors of platelet did not increase. The present case is a rare case of MDS with remarkable thrombocytosis. Her thrombocytosis may have been caused by neoplastic increase of megakaryocyte and platelet in bone marrow.
URI: http://hdl.handle.net/10564/104
ISSN: 13450069
Appears in Collections:Vol.54 No.2

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