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Vol.54 No.2 >
Please use this identifier to cite or link to this item:
http://hdl.handle.net/10564/100
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Title: | Relationship of Metallothionein to Zinc Metabolism During Pregnancy |
Authors: | Minami, Takeshi Naganuma, Takashi Watanabe, Mariko Takemura, Hideo |
Keywords: | metallothionein zinc β2-microgloblin amniotic fluid |
Issue Date: | 30-Apr-2003 |
Publisher: | 奈良医学会 奈良県立医科大学 |
Citation: | Journal of Nara Medical Association Vol.54 No.2 p.77-82 |
Abstract: | The amounts of metallothionein (MT) and related substances in amniotic fluid and urine were measured, and the role of the MT contained in these fluids was studied. Amniotic fluid without blood was collected during Caesarian sections. Total urine
obtained during one day was collected from newborn infants (0-6 days), and spot urine
was collected from pregnant women. Sera were also collected. MT in amniotic fluid and urine was measured by radioimmunoassay. In amniotic fluid, a positive relation was
observed between MT and β2-microgloblin (MG), but not between MT and zinc. In contrast, a positive relation was observed between MT and zinc in urine of newborn
infants, but not between MT and MG. Serum zinc levels were significantly lower in
postpartum women than healthy young women, and urinary zinc levels were markedly higher in newborn infants than healthy young women. In conclusion, the level of MT in amniotic fluid may reflect fetal renal function, and another function of MT in the fetus and newborn infant is to supplement zinc in the body. |
URI: | http://hdl.handle.net/10564/100 |
ISSN: | 13450069 |
Appears in Collections: | Vol.54 No.2
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