DSpace コレクション: 2000-02
http://hdl.handle.net/10564/1536
2000-022024-03-28T11:34:41Z腹部造影CTとカラードプラエコーが診断に有用であった腎梗塞の2例
http://hdl.handle.net/10564/588
タイトル: 腹部造影CTとカラードプラエコーが診断に有用であった腎梗塞の2例
著者: 那須, 賢哉; 林, 照剛; 勝山, 慶之; 酢谷, 俊夫; 中野, 智幸; 平井, 純; 川本, 篤彦; 土肥, 和紘
抄録: We report two cases of renal infarction. Case 1 involved a 49-year-old man
wht complained of left back pain. Case 2 involved a 50-year-old woman who had suffered
from hypertension for ten years and had experienced a myocardial infarction 5 years
previously and a cerebral infarction 4 years before her admission with right flank pain.
In both cases, contrast-enhaneed CT scan and color Doppler ultrasound demonstrated a
hypoperfused area of the kidney, and both patients were diagnosed with renal infarction.
Urokinase and heparin were administered intravenously in both cases. In case 1, contrast
-enhanced CT scan and color Doppler ultrasound performed one week after admission
revealed improved arterial blood flow in the infarct area. In case 2, the same tests
performed after one week demonstrated no improvement in renal arterial blood flow.
In conclusion, contrast-enhanced CT scan and color Doppler ultrasound are useful in
distinguishing renal infarction from other forms of acute abdomen.2000-02-28T15:00:00ZCAPDに合併した胸水貯留に対して自己血注入による胸膜癒着術が有効であった1例
http://hdl.handle.net/10564/587
タイトル: CAPDに合併した胸水貯留に対して自己血注入による胸膜癒着術が有効であった1例
著者: 川野, 貴弘; 京田, 有輔; 団野, 大介; 中川, 陽子; 山路, 國弘; 丸山, 直樹; 久我, 由紀子; 西岡, 久之; 後一, 肇; 西浦, 公章
抄録: We report a case of hydrothorax in a patient undergoing continuous
ambulatory peritoneal dialysis (CAPD) who was treated with autologous blood pleurodesis.
A 46-year-old woman with end-stage renal failure due to IgA nephropathy started CAPD
on February 9, 1994. After 19 days, she was admitted to our hospital because of dyspnea.
A chest X-ray revealed right pleural effusion. Pleuroperitoneal communication was
diagnosed because the glucose concentration in the pleural fluid was high compared with
that in her blood. Autologous blood pleurodesis was performed after drainage of the pleural
effusion. After 4 weeks, CAPD was restarted, and hydrothorax did not recur. Autologous
blood pleurodesis may be useful in the treatment of hydrothorax in a patient receiving
CAPD.2000-02-28T15:00:00Z通過静脈皮弁移植の実験的研究とその臨床応用
http://hdl.handle.net/10564/586
タイトル: 通過静脈皮弁移植の実験的研究とその臨床応用
著者: 平井, 利幸; 福居, 顕宏; 玉井, 進; 稲田, 有史
抄録: In recent years, conventional flaps which make a sacrifice of main arteries
as reported frequently in the early stage of their development have been reevaluated in the
field of flap surgery. This movement has facilitated development of flaps vascularized by
perforating branches measuring about 0.3 mm in diareter, and has also thrown light on the
merits of venous flaps which make no sacrifice of main arteries. Looking back on the
history of venous flaps, they initially attracted attention because, in contrast to conven-
tional flaps, 1) they do not make a sacrifice of main arteries, 2) they are not limited by
the conditions of the recipient site, and 3) preparation of the flap is technically easy and
applicable to emergency operations. Because of these advantages, venous flaps have been
used widely in the clinical setting, but the mechasism of flap survival remains conjectural.
The present study was designed to determine the limits of venous flap viability supplied by
one vein, which is one of the questions related to venous flap stirvival. A flom-through
venous flap measuring 3.0×3.0 cm was prepared in the lateral margin of the auricle in
rabbits, and the area of flap viability was determined. The influences of surrounding blood
circulation on the area of flap viability were also investigated. As a result the width of flap
covered by one vein was 11.0±4.8 mm as a whole, whereas it was 18.1±6.2 mm in the
presence of good blood circulation in the surroundings, showing a significant effect of
surrounding blood circulation. Based on these experimental data, flow-through venous
flaps were applied to 25 patients and the stability of the flaps was confirmed. The presence
of arteriolar systems in perivenous tissues has been demonstrated recently. To provide the
venous flap with blood flow from the arteriolar system is another way to improve the
viability of venous flaps.2000-02-28T15:00:00Zヒト型結核菌に対するマウス系統間における抵抗性及び肺病変の比較
http://hdl.handle.net/10564/585
タイトル: ヒト型結核菌に対するマウス系統間における抵抗性及び肺病変の比較
著者: 油納, 善久
抄録: Five inbred strains of mice were examined for resistance to intravenous
infection with 10^5 colony-forming units of Mycobacterium tuberculosis H37Rv. Based on the
difference in survival time, five strains were classified into two groups : susceptible (CBA
and DBA/2) and resistant (BALB/c, A/J, C57BL/6) strains. After infection with M.
tuberculosis, mycobacteria rapidly multiplied in the lung with low levels of pulmonary IL-
12 production in CBA mice ; resulting in the progression of necrotic pneumonia. In contrast,
mycobacteria slowly multiplied in association with high levels of IL-12 production in the
lung of C57BL/6 mice ; leading to the development of granulomas. In C57BL/6 mice, the
growth of bacteria was suppressed over a long period (6th-24th weeks) after infection, and
granulomatous response in the lung was followed by progressive fibrosis capable of prevent-
ing bacterial dissemination. When alveolar macrophages from both strains were infected
in vitro with M. tuberculosis at a ratio of 1 : 10, the degree of phagocytic activity was not
different between two strains, but C57BL/6 cells displayed higher anti-mycobacterial
activity compared to CBA cells. These results suggest that murine natural resistance
against M. tuberculosis depends on the anti-mycobacterial activity of alveolar macrophages,
and the early production of IL-12 in the lung upon infection appears to be associated with
the innate resistance and subsequent induction of M. tuberculosis-specific immunity.
Moreover, vaccination with BCG was effective in reducing bacterial growth in both mouse
strains during the initial phase of infection, while its effect was expressed in only resistant
mice as the retardation of histopathologic progression during the late phase.2000-02-28T15:00:00Z