DSpace コレクション: 1997-12
http://hdl.handle.net/10564/1521
1997-122024-03-29T07:43:45Z第118回奈良医学会 : 学会記事
http://hdl.handle.net/10564/413
タイトル: 第118回奈良医学会 : 学会記事1997-12-30T15:00:00Z血行性腎カンジダ症による急性腎不全を合併した胃幽門部癌の1例
http://hdl.handle.net/10564/412
タイトル: 血行性腎カンジダ症による急性腎不全を合併した胃幽門部癌の1例
著者: 川田, 啓之; 西野, 俊彦; 椎木, 英夫; 川本, 篤彦; 金内, 雅夫; 土肥, 和紘; 藤尾, 陽一
抄録: A 67-year-old man was referred to our hospital because of high-grade fever
and acute renal failure on January 11, 1996. Gastroduodenal fiberscopy performed 17 days
before admission revealed advanced gastric cancer in the pylorus. Intravenous hyper-
alimentation was started on December 27, 1995. Because of the fever, the patient had been
treated with 5mg/day of indomethacin and 2g/day of cefazolin since January 1, 1996.
Serum creatinine was elevated to 8.2mg/dl. To rule out acute interstitial nephritis caused
by these drugs, a renal biopsy was performed on the second hospital day. The biopsy
specimen demonstrated multiple microabscesses containing yeast-like organisms in the
medulla. Candida tropicalis was isolated from urine cultures, atrial blood and the catheter
tip. The patient was diagnosed as having acute renal failure due to renal candidiasis. Under
hemodialysis treatment, he received 400mg/day of miconazole. Hemodialysis was stopped
on the 13th hospital day. On the 41st hospital day, the patient was afebrile and serum
creatinine had decreased to 1.7mg/dl. We present a case of acute renal failure due to renal
moniliasis caused by hematogenous infection with Candida tropicalis, and discuss the
related literature.1997-12-30T15:00:00Z90歳女性の巨大腹壁膿瘍を合併した結腸癌の1例
http://hdl.handle.net/10564/411
タイトル: 90歳女性の巨大腹壁膿瘍を合併した結腸癌の1例
著者: 久我, 由紀子; 藤井, 謙裕; 山野, 繁; 橋本, 俊雄; 土肥, 和紘; 福岡, 喜晃; 小西, 陽一
抄録: A 90-year-old female was admitted to our hospital because of fever and
swelling in the left lower quadrant. There were severe hypoproteinemia and inflammatory
reaction in her laboratory data. Giant abscess formation in the abdominal wall was
revealed by ultrasonography and CT scan. About 2,000ml volume discharge from the
abscess was evident on the surgical drainage. Bacteroides, Fusobacterium, Enterobacter-
iaceae and Escherichia coli were detected by the culture from the abscess. Colonoscopy
revealed a sigmoid colon cancer. In the course of the conservative treatment, a discharge
with feces from the abscess was evident. This patient was found to have a giant abscess
of abdominal wall due to development of sigmoid colon cancer.1997-12-30T15:00:00ZNITRIC OXIDE SYNTHASE INHIBITOR SUPPRESS THE VASOCONSTRIC-TION DUE TO SEVOFLURANE IN CEREBRAL PIAL ARTERIES LARGER THAN 100μm IN DIAMETER IN CATS
http://hdl.handle.net/10564/410
タイトル: NITRIC OXIDE SYNTHASE INHIBITOR SUPPRESS THE VASOCONSTRIC-TION DUE TO SEVOFLURANE IN CEREBRAL PIAL ARTERIES LARGER THAN 100μm IN DIAMETER IN CATS
著者: Syohda, Asao
抄録: Background Nitric oxide (NO) plays an important role in the reactivity of
cerebral circulation to various stimuli. It is still unclear whether NO mediates the effect of
sevoflurane on cerebral circulation. We therefore examined this question by measuring the
diameter of pial arteries with or without exposure to NO synthase inhibitor, N ω-nitro-L
-arginine methyl ester (L-NAME).
Methods The cranial window technique was employed in experiments using seven cats that
received fentanyl and midazolam under mechanical ventilation. Diameters of cerebral pial
arteries were observed through the cranial windows using an incident-light fluorescence
microscope and video-recorded with a silicon-intensified target tube video camera system.
Changes in arterial diameter were measured with an image analyzer after the experiments
were finished. The diameters of pial arteries were measured under four conditions follow-
ing the protocol below : 1) intravenous anesthesia ; 2) intravenous plus sevoflurane anesthe-
sia; then after L-NAME infusion, 3) intravenous anesthesia ; and 4) intravenous plus
sevoflurane anesthesia. Changes in vessel diameter were analyzed.
Results The arteries larger than 100μm were significantly constricted (p<0.05) under
sevoflurane inhalation ; in contrast, after the administration of L-NAME, the arteries were
not significantly affected by sevoflurane inhalation.
Conclusion L-NAME inhibited the vasoconstriction due to sevoflurane inhalation in cere-
bral pial arteries larger than 100μm. In the cerebral pial arteries larger than 100μm in
diameter, NO synthesis was shown to be involved in vasoconstriction due to sevoflurane
inhalation.1997-12-30T15:00:00Z