DSpace コレクション: 1992-081992-08http://hdl.handle.net/10564/18792024-03-29T09:56:39Z2024-03-29T09:56:39Z動静脈間シャントが循環動態におよぼす影響 :動物実験ならびに臨床症例による検討平井, 純http://hdl.handle.net/10564/18982017-05-29T06:07:51Z1992-08-30T15:00:00Zタイトル: 動静脈間シャントが循環動態におよぼす影響 :動物実験ならびに臨床症例による検討
著者: 平井, 純
抄録: The experimental and clinical studies were carried out to clarify the effects of arteriovenous shunt (AVS) on cardiac hemodynamics and organic circulation. In the experimental study using 7 mongrel dogs, AVS was made between the femoral artery and vein, and its blood flow was regulated equivalent to 20% of cardiac output. Changes
in cardiac hemodynamics and in organic circulation especially in renal one, due to opening and closing AVS were observed. In the clinical study for 10 patients with end-stage renal disease, their cardiac hemodynamics were evaluated before and after the AVS formation by echocardiography and mechanocardiography. For the experimental study, opening AVS induced a slight decrease in total peripheral vascular resistance, significant increase in cardiac output, transient descent in aortic blood pressure, and ascent in inferior caval pressure. And a transient fall in renal blood pressure was observed, neither renal blood flow nor renal vascular resistance were changed. Recovery of cardiac hemodynamic indices due to closing AVS were delayed as compared with renal circulatory ones. For the clinical study, the increase in stroke volume, minute
cardiac output and mean circumferential fiber shortening velocity of the left ventricle were observed after AVS formation.
It seems that the AVS caused a hyperkinetic circulatory state with increase in venous
return and consequent increase in cardiac contractility. Therefore, it must be careful that the hyperkinetic state mentioned above may bring a high output heart failure.1992-08-30T15:00:00Z本態性低血圧症の心機能に関する研究 : 交感神経α₁受容体・β受容体刺激薬に対する反応性松本, 善孝http://hdl.handle.net/10564/18972017-05-29T06:07:57Z1992-08-30T15:00:00Zタイトル: 本態性低血圧症の心機能に関する研究 : 交感神経α₁受容体・β受容体刺激薬に対する反応性
著者: 松本, 善孝
抄録: In order to evaluate the cardiovascular function of patients with essential hypotension, systolic time intervals (STI) in 25 essential hypotensives (Group EH) and 100 healthy adults (Group C) were measured. There were no differences in STI between Group EH and Group C. Furthermore, methoxamine or isoproterenol was intravenously administrated in 15 essential hypotensives (Group L), and 10 healthy volunteers (Group N) for further evaluation of cardiovascular function. Left ventricular ejection time (LVET) of Group L was significantly prolonged and LVET/PEP (PEP ; pre-ejection period) of Group L was elevated compared to those of Group N by infusion of methoxamine, suggesting that cardiac pump function may be accelerated in Group L. When isoproterenol was loaded, LVET of Group N was shortened but LVET of Group L was not changed. The effect of methoxamine on cardiovascular function in Group L may be due to augmentation of contractility of myocardium rather than constriction of resistant vessels through α₁ receptor.1992-08-30T15:00:00Z地域集団健診で得られた血圧値の性状とその関連要因に関する横断研究車谷, 典男榎本, 康博大門, 位守和田, 昭治森山, 忠重川口, 忠男杉本, 和夫http://hdl.handle.net/10564/18962017-05-29T06:07:51Z1992-08-30T15:00:00Zタイトル: 地域集団健診で得られた血圧値の性状とその関連要因に関する横断研究
著者: 車谷, 典男; 榎本, 康博; 大門, 位守; 和田, 昭治; 森山, 忠重; 川口, 忠男; 杉本, 和夫
抄録: To clarify the characteristics of blood pressure and to investigate the association with its relevant factors we performed a cross-sectional study for people participating voluntarily in community-based mass examinations in three villages in Nara Prefecture in Summer, 1991. The subjects involved in this study were 1,654 (647 men and 1,007 women) aged from 40 to 69. Mean systolic blood pressure (SBP) and diastolic blood pressure (DBP) of the men were 126.2 (SD 17.2) mmHg and 76.1 (10.9) mmHg, respectively. Those of the women were 124.5 (18.2) mmHg and 73.4 (10.1) mmHg. The prevalence of persons judged to be hypertensive by WHO's criteria were 6.2% for the men and 4.1% for the women. These figures are much smaller than the corresponding figures in other epidemiologic studies in Japan. The differences may reflect selection bias of the subjects in this study. Both serum total cholesterol (TC) and high density lipoprotein cholesterol (HDL) levels associated with gender, age and body shape type (BST) index. The TC level among obese people was significantly higher than that of thin people. On the contrary, the HDL level showed significantly higher mean value among the thin people than the obese. Multiple regression analysis on SBP indicated that BST index, age, TC and gender had significant partial regression coefficients while village and HDL did not. The older, obese men with a higher TC level are likely to have higher SBP. Also the obese men with a higher TC level were found to be likely to have higher DBP. These results suggest that BST and TC should be independent risks for increase in SBP and DBP. Intervention in obesity can be a advisable way for both prevention and treatment of hypertension.1992-08-30T15:00:00Z骨盤内臓全摘術9例の検討佐道, 三郎藤井, 久男山本, 克彦山本, 雅敏吉川, 周作内藤, 梓渡邉, 巌仲川, 昌之中嶋, 寿西川, 徹森田, 敏裕中野, 博重http://hdl.handle.net/10564/18952017-05-29T06:07:51Z1992-08-30T15:00:00Zタイトル: 骨盤内臓全摘術9例の検討
著者: 佐道, 三郎; 藤井, 久男; 山本, 克彦; 山本, 雅敏; 吉川, 周作; 内藤, 梓; 渡邉, 巌; 仲川, 昌之; 中嶋, 寿; 西川, 徹; 森田, 敏裕; 中野, 博重
抄録: Among 110 patients treated for rectal malignancy during the last 7 years, nine patients underwent pelvic exenteration, total pelvic exenteration for 7, posterior pelvic exenteration for 2. These patients, 6 men and 3 women, had a mean age of 53 years.
Primary surgical therapy was made in 56%, and secondary in 44%. Operative mortality was 11%. Duration after operation ranged from 65 months to 5 months. One patient died
in 8 surviving the operation, the recurrence rate for these 8 patients was 62.5%. Secondary curative resection was made for 40% in the recurrent patients. Pelvic exenteration is reasonable primary surgical therapy in selected patients with large bulky locally invasive rectal malignancies that can be removed en bloc. Futhemore, this procedure can be curative and often is palliative for similar that are recurrent patients.1992-08-30T15:00:00Z