2024-03-29T10:22:59Zhttp://ginmu.naramed-u.ac.jp/dspace-oai/request
oai:ginmu.naramed-u.ac.jp:10564/19762017-06-11T23:20:26Zhdl_10564_1975表紙、目次、訂正、投稿規定、奥付(Vol.42 No.3)表紙目次訂正投稿規定奥付奈良医学会OtherOthersapplication/pdf奈良医学雑誌 Vol.42 No.30469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1976奈良医学雑誌, 42(3)http://hdl.handle.net/10564/1976http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1976/1/%e8%a1%a8%e7%b4%99%e3%80%81%e7%9b%ae%e6%ac%a1%e3%80%81%e8%a8%82%e6%ad%a3%e3%80%81%e6%8a%95%e7%a8%bf%e8%a6%8f%e5%ae%9a%e3%80%81%e5%a5%a5%e4%bb%98%28Vol.42_No.3%29.pdf04695550AN00180974奈良医学雑誌4231991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19772017-06-11T23:20:26Zhdl_10564_1975血友病A保因者のRestriction fragment length polymorphism(RFLP)解析 : Ⅰ. 正常女性における第Ⅷ因子遺伝子内RFLPRESTRICTION FRAGMENT LENGTH POLYMORPHISM ANALYSIS IN HEMOPHILIA A CARRIERS Ⅰ. ANALYSIS OF POLYMORPHISMS IN FACTOR Ⅷ GENE IN NORMAL FEMALES中, 宏之factor Ⅷ genehemophilia Arestriction fragment length polymorphism (RFLP)The restriction fragment length polymorphisms of factor Ⅷ gene in 35 normal subjects (5 males and 30 females) were analysed by Southern blot technique. Polymorphism by the BclⅠ digestion detected the smaller allele (0.8 kb) in 86.2% and the
larger allele (1.2 kb) in 13.8% of normal 65 X chromosomes. Heterozygosity rate of BclⅠ RFLP was 26.7% in 30 normal females. Polymorphism by the XbaⅠ digestion detected
the smaller allele (1.4 kb) in 60% and the larger allele (6.2 kb) in 40% in normal 65 X
chromosomes. Heterozygosity rate of XbaⅠ RFLP was 63% in 30 normal females. Polymorphism by the BglⅠ digestion detected the smaller allele (5.0 kb) in 86.2% and the
larger allele (20.0 kb) in 13.8% in the normal 65 X chromosomes. Heterozygosity rate of BglⅠ RFLP was 23.3% in 30 normal females. Polymorphism by the Hind Ⅲ or Msp Ⅰ digestion detected the smaller allele (2.6 kb or 4.3 kb) in 13.8% and the larger allele (2.7 kb or 7.5 kb) in 86.2% in normal 65 X chromosomes. The combination of BclⅠ and XbaⅠ RFLPs was most effective and useful, and detected informativerly 66.7% heterozygosity in 30 normal females. It was suggested that hemophilia A families could be analyzed by these RFLPs.奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.173-1810469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1977奈良医学雑誌, 42(3): 173-181http://hdl.handle.net/10564/1977http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1977/1/173-181p%ef%bc%9a%e8%a1%80%e5%8f%8b%e7%97%85A%e4%bf%9d%e5%9b%a0%e8%80%85%e3%81%aeRestriction_fragment_length_polymorphism%28RFLP%29%e8%a7%a3%e6%9e%90%e2%85%a0.%e6%ad%a3%e5%b8%b8%e5%a5%b3%e6%80%a7%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e7%ac%ac%e2%85%a7%e5%9b%a0%e5%ad%90%e9%81%ba%e4%bc%9d%e5%ad%90%e5%86%85RFLP.pdf04695550AN00180974奈良医学雑誌4231731811991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19782017-06-11T23:20:26Zhdl_10564_1975血友病A保因者のRestriction fragment length polymorphism(RFLP)解析 : Ⅱ. 血友病A家系における保因者診断RESTRICTION FRAGMENT LENGTH POLYMORPHISM ANALYSIS IN HEMOPHILIA A CARRIERS Ⅱ. CARRIER DETECTION IN HEMOPHILIA A FAMILIES中, 宏之carrier detectionRFLPhemophilia Afactor Ⅷ geneCarriers of hemophilia A were detected in 30 families by means of five intragenic and one extragenic restriction fragment length polymorphisms. The heterozygosity rates of BclⅠ RFLP, XbaⅠ RFLP, BglⅠ RFLP, Hind Ⅲ RFLP, and MspⅠ RFLP were 23.3%, 60.0%, 10.0%, 23.3%, and 23.3% respectively in 30 hemophilia A mothers. The combination of BclⅠ and XbaⅠ RFLPs was most effective and useful, and detected informatively 63.3% heterozygosity in 30 hemophilia A mothers. In 17 of 30 hemophilia A mothers (56.7%), the extragenic factor Ⅷ, ST14-1 probe, was useful for carrier detection. The combination of BclⅠ RFLP, XbaⅠ RFLP and ST14-1 probe detected 26 carriers in 30
hemophilia A mothers (86.7%). The examples of carrier detection by RFLPs are presented
in three families of hemophilia A.奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.182-1900469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1978奈良医学雑誌, 42(3): 182-190http://hdl.handle.net/10564/1978http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1978/1/182-190p%ef%bc%9a%e8%a1%80%e5%8f%8b%e7%97%85A%e4%bf%9d%e5%9b%a0%e8%80%85%e3%81%aeRestriction_fragment_length_polymorphism%28RFLP%29_%e8%a7%a3%e6%9e%90%e2%85%a1.%e8%a1%80%e5%8f%8b%e7%97%85A%e5%ae%b6%e7%b3%bb%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e4%bf%9d%e5%9b%a0%e8%80%85%e8%a8%ba%e6%96%ad.pdf04695550AN00180974奈良医学雑誌4231821901991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19792017-05-29T06:07:58Zhdl_10564_1975臓器循環に関する研究 : ANP投与が諸臓器循環動態におよぼす影響HEMODYNAMIC EFFECTS OF BOLUS ADMINISTRATION OF ATRIAL NATRIURETIC PEPTIDE IN ANESTHETIZED DOGS中谷, 晃野中, 秀郎anesthetized dogsatrial natriuretic peptideregional hemodynamicssystemic hemodynamicsA study was perfomed on anesthetized dogs to determine the effects of three doses of synthetic atrial natriuretic peptide (ANP) on systemic and regional hemodynamics. ANP produced falls in mean aortic blood pressure for all doses : 0.1 μg・kg⁻¹(low dose), 0.5 μg・kg⁻¹(medium dose), and 2.5 μg・kg⁻¹(high dose). With medium and high doses, a transient decrease in total peripheral resistance and a similar increase in cardiac output (CO) were observed the stage immediately following administration of ANP. Marked but transient increases in carotid blood flow was observed after administration of all three doses of ANP. Furthermore, ANP caused transient decreases in carotid vascular resistance, while carotid blood flow increased more markedly than CO. On the other hand, organ blood flow to the splanchnic organs and skeletal muscles decreased or tended to decrease. This study demonstrates that (1) ANP mediated reduction in aortic blood pressure creates a decrease in total peripheral resistance, (2) ANP most effectively relaxes the carotid artery, and (3) the hepatic, mesenteric and femoral arteries are less sensitive to ANP.奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.191-2050469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1979奈良医学雑誌, 42(3): 191-205http://hdl.handle.net/10564/1979http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1979/1/191-205p%ef%bc%9a%e8%87%93%e5%99%a8%e5%be%aa%e7%92%b0%e3%81%ab%e9%96%a2%e3%81%99%e3%82%8b%e7%a0%94%e7%a9%b6.pdf04695550AN00180974奈良医学雑誌4231912051991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19802017-05-29T06:07:54Zhdl_10564_1975新たな尿意の獲得を目的とした回腸開放弁膀胱固定術における実験的研究AN EXPERIMENTAL STUDY OF ACQUIREMENT OF URINARY SENSATION THROUGH AN ILEAL FLAP FIXATION TO THE BLADDER末盛, 毅ileal flap fixationneurogenic bladdersubstitute urinary sensationadult female mongrel dogWe have previously reported about a surgical procedure, ileal flap fixation to the urinary bladder, to obtain a new voiding desire in children with congenital neurogenic
bladder mainly due to spina bifida cystica, and have demonstrated satisfactory results by
the procedure. The present study was conducted to physiologically elucidate the mechanism of development of the new voiding desire by the procedure by using adult female mongrel dogs. Histopathological examinations failed to reveal communication between nerves of the ileum and the urinary bladder or regeneration of nerves in the ileal flap. However, physiological examinations showed an increase in the electric activity of the mesenteric splanchnic nerve on full bladder at the portion close to the attached site of the
ileal flap, and an electroneurogram of the nerve was successfully introduced. The data suggest that the extension of the ileum wall fixed to the bladder resulted in the substitute urinary sensation as the new voiding sensation which was transmitted via the vagus and splanchnic nerves of the large or small intestine.奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.206-2130469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1980奈良医学雑誌, 42(3): 206-213http://hdl.handle.net/10564/1980http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1980/1/206-213p%ef%bc%9a%e6%96%b0%e3%81%9f%e3%81%aa%e5%b0%bf%e6%84%8f%e3%81%ae%e7%8d%b2%e5%be%97%e3%82%92%e7%9b%ae%e7%9a%84%e3%81%a8%e3%81%97%e3%81%9f%e5%9b%9e%e8%85%b8%e9%96%8b%e6%94%be%e5%bc%81%e8%86%80%e8%83%b1%e5%9b%ba%e5%ae%9a%e8%a1%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e5%ae%9f%e9%a8%93%e7%9a%84%e7%a0%94%e7%a9%b6.pdf04695550AN00180974奈良医学雑誌4232062131991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19812017-05-29T06:07:58Zhdl_10564_1975急性単球性白血病を発症したピルビン酸キナーゼ欠乏症の1例A CASE OF PYRUVATE KINASE DEFICIENCY ASSOCIATED WITH ACUTE MONOCYTIC LEUKEMIA森田, 博文土肥, 和紘布谷, 隆治岡林, 正純石川, 兵衞下山, 丈人小西, 登acquired enzymatic deficiencyhemolytic anemiapreleukemiapyruvate kinase deficiencyA case of pyruvate kinase deficiency anemia associated with acute monocytic leukemia is reported with a review of the literature. A 57-year-old man who was treated for diabetes mellitus at a nearby hospital was admitted to our hospital for precise examination of the progression of anemia. Blood examination showed RBC 207×10⁴/μl, Hb 5.9 g/dl, Ht 18%, reticulocytes 134‰, WBC 5,200/μl, platelets 9.3×10⁴/μl, indirect bilirubin 0.6 mg/dl, serum iron 112 μg/dl, haptoglobin
under 10 μg/dl. After admission to our hospital, serum indirect bilirubin level was increased to 2.3 mg/dl, and pancytopenia was noted in the peripheral blood. the half life span of erythrocytes had shortened to 16 days. A bone marrow examination revealed prominent erythroid hyperplasia. More detailed examination of this hemolysis revealed pyruvate kinase deficiency of erythrocytes. Three months after admission, blast cells were noted in the peripheral blood and they increased progressively. The bone marrow contained 43.6% of blast cells. Subsequently, a diagnosis of acute monocytic leukemia was made. Although intensive chemotherapy was performed, the patient achieved no remission and died 6 months after admission to our hospital.奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.214-2200469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1981奈良医学雑誌, 42(3): 214-220http://hdl.handle.net/10564/1981http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1981/1/214-220p%ef%bc%9a%e6%80%a5%e6%80%a7%e5%8d%98%e7%90%83%e6%80%a7%e7%99%bd%e8%a1%80%e7%97%85%e3%82%92%e7%99%ba%e7%97%87%e3%81%97%e3%81%9f%e3%83%94%e3%83%ab%e3%83%93%e3%83%b3%e9%85%b8%e3%82%ad%e3%83%8a%e3%83%bc%e3%82%bc%e6%ac%a0%e4%b9%8f%e7%97%87%e3%81%ae1%e4%be%8b.pdf04695550AN00180974奈良医学雑誌4232142201991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19822017-05-29T06:07:48Zhdl_10564_1975糖尿病性腎症の早期診断に対するアルギニン負荷試験の有用性DIAGNOSTIC SIGNIFICANCE OF ARGININE LOADING TEST IN THE EARLY STAGE OF DIABETIC NEPHROPATHY金内, 雅夫土肥, 和紘西浦, 公章中島, 靖夫石井, 健司川野, 貴弘石原, 京子石川, 兵衞arginine loading testdiabetic nephropathyrenal biopsyurinary albuminDiagnostic significance of arginine loading test in the early stage of diabetic nephropathy is evaluated in relation to the histological findings of renal biopsy specimens. The subjects were 30 diabetics, divided into 3 groups (D0, DⅠ and DⅡ) according to the stage of glomerular diffuse lesion based on Gellman's criteria. Glomerular filtration rate (GFR), urinary albumin and urinary β2 microglobulin (β2MG) were measured before and after 30 g arginine loading by intravenous infusion. Before arginine loading, GFR was significantly lower in DⅠ and DⅡ than in D0, the excretion of urinary albumin was significantly higher in DⅡ than in D0, and the excretion of urinary β2MG was significantly higher in DⅡ than in D0 and DⅠ. After arginine loading, GFR was significantly lower in DⅡ than in D0, and the excretion of urinary albumin was significantly higher in DⅠ and DⅡ than in D0, however, no significant difference was seen in the excretion of urinary β2MG among these three groups. These results suggest that the arginine loading test is one useful method for diagnosis of early diabetic nephropathy.奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.221-2250469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1982奈良医学雑誌, 42(3): 221-225http://hdl.handle.net/10564/1982http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1982/1/221-225p%ef%bc%9a%e7%b3%96%e5%b0%bf%e7%97%85%e6%80%a7%e8%85%8e%e7%97%87%e3%81%ae%e6%97%a9%e6%9c%9f%e8%a8%ba%e6%96%ad%e3%81%ab%e5%af%be%e3%81%99%e3%82%8b%e3%82%a2%e3%83%ab%e3%82%ae%e3%83%8b%e3%83%b3%e8%b2%a0%e8%8d%b7%e8%a9%a6%e9%a8%93%e3%81%ae%e6%9c%89%e7%94%a8%e6%80%a7.pdf04695550AN00180974奈良医学雑誌4232212251991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19832017-05-29T06:07:48Zhdl_10564_1975小児十二指腸Leiomyoblastomaの1例A 14-YEAR-OLD GIRL WITH LEIOMYOBLASTOMA IN THE DUODENUM久世, 晋徳宮田, 茂樹武田, 以知郎山下, 隆司上辻, 秀和山田, 貴本郷, 三郎富田, 令子徳田, 晴厚岩垣, 克己leiomyoblastoma duodenal tumorLeiomyoblastoma, which shows caracteristic pathological features among myogenic tumors, is observed in the uterus as in the whole area of the gastroistestinal tract including the stomach. We recently experienced a case of leiomyoblastoma of the duodenum and here discuss the case with reference to 12 cases previously reported in Japan. A 14-year-old girl with a chief complaint of vomiting was referred to our hospital for further evaluation of an abdominal mass. Upper gastrointestinal X-ray showed a giant tumor on the third portion of the duodenum. A metastatic tumor was recognized in the liver on CT-scan. Duodenectomy was performed. Histology of resected specimen showed Leiomyoblastoma. In the Japanese literature Leiomyoblastoma of the duodemum is rare and has had a greater tendency to be malignant than leiomyoblastoma of the stomach. In our case, the tumor originated in the duodenum and metastatic tumor was observed in the liver. Therefore we considered she should be kept under close medical observation.奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.226-2300469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1983奈良医学雑誌, 42(3): 226-230http://hdl.handle.net/10564/1983http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1983/1/226-230p%ef%bc%9a%e5%b0%8f%e5%85%90%e5%8d%81%e4%ba%8c%e6%8c%87%e8%85%b8Leiomyoblastoma%e3%81%ae1%e4%be%8b.pdf04695550AN00180974奈良医学雑誌4232262301991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19842012-02-16T06:20:21Zhdl_10564_1975機能性甲状腺癌の一例A CASE OF FUNCTIONING CARCINOMA OF THE THYROID西山, 利正岡本, 新悟富永, 謙太郎細川, 彰子梅本, 典江泉, 由紀子福井, 博辻井, 正田中, 治松永, 喬日浅, 義雄functioning thyroid carcinomafollicular carcinomaA 62-year-old woman with large tumor of the thyroid manifesting thyrotoxicosis is presented. Thyroid function tests showed a slight hyperthyroidism. Radiolabelled iodine accumulated in some parts of the tumor and the others were cold. Triiodothyronin (l-T_3) administration showed non-suppression of the hot pattern. Moreover the blood thyroxin level was not lowered following the suppression of thyrotropin (TSH) induced by
l-T_3 administration. A total tumorectomy was performed and the pathological examination showed various degrees of follicular carcinoma. Histological findings were compared to the radiolabelled iodine uptake by mapping of thyroid scintigram. The most highly accumulated area of radiolabelled iodine consisted of smaller follicles with coloid. However, the unaccumulated areas consisited of cancer cells simulated in fetal thyroid or solid and trabecular patterns. This clinical evidence indicates that thyrotoxicosis in this case is caused by the excessive secretion of thyroid hormones from which were produced the cancer cells of highly accumulated area of radiolabelled iodine.個人の特定が出来ると思われる写真が掲載されているため本文PDFの登録はなし奈良医学会ArticleDepartmental Bulletin Papertext/plain奈良医学雑誌 Vol.42 No.3 p.231-2390469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1984奈良医学雑誌, 42(3): 231-239http://hdl.handle.net/10564/198404695550AN00180974奈良医学雑誌4232312391991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19852012-02-16T07:49:21Zhdl_10564_1975SLEを伴ったKlinefelter症候群の1例A CASE OF KLINEFELTER'S SYNDROME ASSOCIATED WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)泉, 由紀子岡本, 新悟細川, 彰子西山, 利正梅本, 典江辻井, 正村松, 勉三馬, 省二河田, 陽一山田, 一岡島, 英五郎Klinefelter's syndromesystemic lupus erythematosushypogonadismThe case of a 36-year-old male patient with Klinefelter's syndrome associated with systemic lupus erythematosus (SLE) is presented. He was diagnosed as SLE and had been treated since the age of 25 years old. Hypogonadism showing loss of pubic hair and testicular atrophy has appeared since the age of 35. LH-RH test showed a pattern of primary hypogonadism. Karyotype analysis showed that he has 47, XXY chromosomes suggestive of Klinefelter's syndrome. Biopsy of his testis revealed hyaline degeneration of seminiferous tubules and absence of spermatocytes. IgG deposition was found in interstitial cells of testicular tissue by immunohistochemistory. These findings suggest that atrophy of testis is due to immunological changes of SLE as well as hormonal changes of Klinefelter's syndrome.個人の特定が出来ると思われる写真が掲載されているため本文PDFの登録はなし奈良医学会ArticleDepartmental Bulletin Papertext/plain奈良医学雑誌 Vol.42 No.3 p.240-2470469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1985奈良医学雑誌, 42(3): 240-247http://hdl.handle.net/10564/198504695550AN00180974奈良医学雑誌4232402471991-06-30jpnpublisher
oai:ginmu.naramed-u.ac.jp:10564/19862017-05-29T06:07:48Zhdl_10564_1975過去8年間における顎骨内囊胞の臨床統計的観察CLINICO-STATISTICAL OBSERVATION ON JAW CYSTS IN THE LAST 8 YEARS西岡, 博人望月, 光治江口, 陽子竹内, 尚則杉村, 正人堀内, 敬介clinico statistical observationjaw cystodontogenic keratocystClinico-statistical observation was made in patients with jaw cysts referred to the Department of Oral and Maxillofacial Surgery in the last 8 years. Jaw cysts were classified into odontogenic cysts (475 cases, 81.5%) and non-odontogenic cysts (108 cases, 18.5%). Of odontogenic cysts, radicular cysts were seen in 318 (54.5%), residual cysts in 31 (5.3%), follicular cysts in 90 (15.4%), odontogenic keratocysts in 30 (5.1%), non-keratinized primordial cysts in 5 (0.9%) and calcifying odontogenic cysts in 1 (0.2%), respectively. Of non-odontogenic cysts, incisive canal cysts were seen in 5 (0.9%), globulomaxillary cysts in 4 (0.7%), median palatine cysts in 1 (0.2%), postoperative maxillary cysts in 88 (15.1%), traumatic bone cysts in 7 (1.2%) and static bone cavity in 3 (0.5%), respectively. In follicular cysts, the effect of root canal treatment of deciduous teeth on these cysts
was made. Root canal treatment of deciduous teeth was involved in 22 cases (71%) out of
31 cases of follicular cysts. In 30 odontogenic keratocysts, dentigerous type was seen in 13 (43%) and primordial type in 17 (57%).奈良医学会ArticleDepartmental Bulletin Paperapplication/pdf奈良医学雑誌 Vol.42 No.3 p.248-2540469555013450069http://ginmu.naramed-u.ac.jp/dspace/handle/10564/1986奈良医学雑誌, 42(3): 248-254http://hdl.handle.net/10564/1986http://ginmu.naramed-u.ac.jp/dspace/bitstream/10564/1986/1/248-254p%ef%bc%9a%e9%81%8e%e5%8e%bb8%e5%b9%b4%e9%96%93%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e9%a1%8e%e9%aa%a8%e5%86%85%e5%9b%8a%e8%83%9e%e3%81%ae%e8%87%a8%e5%ba%8a%e7%b5%b1%e8%a8%88%e7%9a%84%e8%a6%b3%e5%af%9f.pdf04695550AN00180974奈良医学雑誌4232482541991-06-30jpnpublisher